Dr. Timothy S. Baker

CHEM 165,265 / BIMM 162 / BGGN 262 - 3D Electron Microscopy of Macromolecules
Winter Quarter 2013

Syllabus (PDF)

Book list (PDF)

Reference list (PDF)

The Bottom Line (PDF) -- Key concepts from daily lectures through January 31, 2013

Virtual Homework - Practice Questions for Section I (PDF) Updated January 29, 2013 (Password protected)

Virtual Homework - Practice Questions for Section II (PDF) Updated January 31, 2013 (Password protected)

Required Readings and Optional Movies on CryoEM (Password protected)

Lecture Notes

Sec. IA. Principles of the transmission electron microscope (9.2 MB)
Sec. IB. Design of the transmission electron microscope (3.5 MB)
Sec. IC. Contrast and image formation (692 KB)
Sec. ID. Alignment/adjustment of the microscope (963 KB)
Sec. IE. Operation of the transmission electron microscope (11.1 MB)
Sec. IF. Other modes of TEM operation (3.4 MB)
Sec. IIA. Biological specimen preparation techniques (9.2 MB)
Sec. IIB. Radiation effects (1.4 MB)
Sec. IIIA-C. The structure (5.8 MB)
Sec. IIID. Fourier imaging processing techniques (11.4 MB)

Powerpoint® presentations from lecture (PDFs)

Introduction to the course January 8, 2013 (48 MB)
Lecture #1 January 8, 2013 (15.5 MB)
Lecture #2 January 10, 2013 (4.3 MB)
Lecture #3 January 15, 2013 (20.8 MB)
Lecture #4 January 17, 2013 (9.9 MB)
Lecture #5 January 22, 2013 (17.5 MB)
Lecture #6 January 24, 2013 (26.2 MB)
Lecture #7 January 29, 2013 (67.3 MB)
Lecture #8 January 31, 2013 (47.0 MB)

Date Modified: February 8, 2013